Céu Figueiredo is an Assistant Professor at the Department of Pathology and Oncology at the Faculty of Medicine of the University of Porto and a Principal Investigator at the Epithelial Interactions in Cancer at Ipatimup.
The long-term goal of our research team is to unravel the contribution of Helicobacter pylori infection and of the gastric microbiota to gastric carcinogenesis. We are investigating how variation in H. pylori virulence factors affects their function and contributes to clinically relevant outcomes. We are also exploring how H. pylori interacts at the gastric epithelial surface with cell-cell junctions and with tyrosine kinase receptors, activating signaling pathways that are important for gastric disease development. A more recent area of work explores the changes of the stomach microbiota along the cascade of events that takes place during gastric carcinogenesis.